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Role of endogenous interleukin-12 (IL-12) in induced and spontaneous relapses of experimental autoimmune encephalomyelitis in mice. Volume 10, numéro 2, June 1999

Auteurs
Rega Institute, University of Leuven, Laboratory of Immunobiology, Minderbroedersstraat 10, B-3000 Leuven, Belgium.
  • Page(s) : 171-80
  • Année de parution : 1999

Abbreviations: EAE: experimental autoimmune encephalomyelitis; CREAE: chronic relapsing EAE; IL-12: interleukin-12; IFN-gamma: interferon-gamma; IFN-gammaR KO: IFN-gamma receptor knock-out; CNS: central nervous system; MS: multiple sclerosis. INTRODUCTION Experimental autoimmune encephalomyelitis (EAE) is an inflammatory and demyelinating disease of the central nervous system (CNS), which serves as the prime animal [...]