Epileptic Disorders
MENUFunctional brain connectivity in electrical status epilepticus in sleep Volume 21, numéro 1, February 2019
Illustrations
Tableaux
- Mots-clés : electrical status epilepticus in sleep (ESES), EEG, coherence, oscillations, phase lag, continuous spike and waves during slow wave sleep (CSWS)
- DOI : 10.1684/epd.2019.1027
- Page(s) : 55-64
- Année de parution : 2019
Electrical status epilepticus in sleep (ESES) is an age-related, self-limited epileptic encephalopathy. The syndrome is characterized by cognitive and behavioral abnormalities and a specific EEG pattern of continuous spikes and waves during slow-wave sleep. While spikes and sharp waves are known to result in transient cognitive impairment during learning and memory tasks performed during the waking state, the effect of epileptiform discharges during sleep on cognition and behavior is unclear. There is increasing evidence that abnormalities of coherence, a measure of the consistency of the phase difference between two EEG signals when compared over time, is an important feature of brain oscillations and plays a role in cognition and behavior. The objective of this study was to determine whether coherence of EEG activity is altered during slow-wave sleep in children with ESES when compared to typically developing children.