ARTICLE
Magnesium level in blood and cerebrospinal fluid of children
with febrile convulsions
Agnieszka Mroczkowska-Juchkiewicz*, Agnieszka Paw
owska-Kamieniak, Andrzej Papierkowski *
dr n. med. Agnieszka Mroczkowska-Juchkiewicz, Klinika
Pediatrii i Gastroenterologii AM, ul. ChodŸki 2, 20-093 Lublin,
Poland
The study was carried out on 49 children admitted to the
Pediatrics Ward. The first group comprised 28 children with
febrile convulsions, and the control group consisted of
21 children. All the children were subject to lumbar puncture
and taken blood samples. They all had normal neurological history.
The Mg level in plasma and cerebrospinal fluid (CSF) was measured
by atomic absorption spectrometry. The mean serum and CSF Mg
concentrations in the febrile convulsions group were significantly
lower than in the control group.
Key words: febrile convulsions, magnesium, cerebrospinal
fluid, plasma
Serum magnesium concentration and urinary fractional excretion
of magnesium in children after epileptic seizures
Agnieszka Paw owska-Kamieniak*, Agnieszka
Mroczkowska-Juchkiewicz, Andrzej Papierkowski
* lek. med. Agnieszka Paw owska-Kamieniak, Klinika Pediatrii
i Gastroenterologii DSK, ul. ChodYki 2, 20-093 Lublin,
Poland
Plasma magnesium concentration and urinary fractional excretion
of magnesium were studied in 32 epileptic children and in
21 healthy children.
Serum magnesium levels and fractional excretion of magnesium were
significantly lower in epileptic children.
The results indicate that magnesium may be an endogenously
occurring neuromodulator in epilepsy and epileptic seizures could
be a manifestation of magnesium depletion. The results also suggest
that kidneys play a major role in magnesium homeostasis.
Key words: epilepsy, childchood, hypomagnesemia,
fractional excretion of magnesium
Diagnostics of latent magnesium deficiency in human organism
using modified magnesium loading test
Janusz Rudziñski*, Lech Walasek, Ma gorzata Jurga
* Dr n. med. Janusz Rudziñski, Klinika Chorób Wewnêtrznych
10 WSzK z P SP ZOZ, ul. Powstañców Warszawy 5,
85-915 Bydgoszcz, Poland
The magnesium deficiency is the most often not diagnosed
electrolytic disorder in the organism and significant in the
pathogenesis of several ailments. Difficulties in diagnostics are
due to lack of easy and reliable methods.
The reliable method accessing Mg deficiency is intravenous
magnesium loading test consisting in intravenous infusion of
30 mmol MgSO4 lasting not less than 8 hours
and denotation of Mg elimination in daily urine. Modifications of
the Mg loading test have consisted in lessening of Mg dose and
shortening time of infusion in comparison with the standard loading
test.
Investigations have been performed on 134 patients
(74 men, 60 women) aged between 20 and 71 (on average
43.4 years of age). The following types of modification of the
Mg loading test have been investigated :
1.30 mmol MgSO4 in 500 ml 5% glucose by
8 hours
2.15 mmol MgSO4 in 500 ml 5% glucose by
8 hours
3.30 mmol MgSO4 in 500 ml 5% glucose by
4 hours
4.15 mmol MgSO4 in 500 ml 5% glucose by
4 hours
Two days later, each patient had the standard Mg loading test
(30 mmol MgSO4 by 8 hours) performed in order
to compare and estimate results obtained in the modified test. By
lowering the Mg dose to 15 mmol administered in intravenous
infusion over 8 hours or by lowering it to 15 mmol and
shortening infusion to 4 hours, it was possible to obtain the
results comparable with the standard Mg loading test (30 mmol
MgSO4 by 8 hours). In contrast, the results
obtained when the time of infusion was shortened to 4 hours
while the dose was maintained at 30 Mg mmol were much lower
versus the standard Mg loading test. Besides, it has been observed
increase of Mg level in blood plasma and much higher Mg elimination
in daily urine and lower Mg retention in the organism. The standard
Mg loading test is a valuable, reliable and repeatable method for
diagnosing latent Mg deficiency. The shortening of Mg intravenous
infusion time period in the modified test requires that the Mg dose
be diminished proportionally.
Key words: latent magnesium deficiency, diagnostics of
magnesium deficiency
Comparison of calcium, magnesium, potassium and sodium contents
of Ginkgo biloba L. leaves from Hungary
É. Stefanovits-Bányai*, Zs. Bertényi-Divinyi, A. S. Kiss, A.
Blázovics N. Koczka, Noémi
* Dr. Eva Stefanovits-Bányai, Szent István University,
Faculty of Food Science, Department of Applied Chemistry,
H-1118 Budapest, Villányi ut 29-31, e-mail :
ebanyai@omega.kee.hu
The aim of our preliminary investigations was to determine the
Ca2+, Mg2+, Na+, K+
cation contents by ICP, cation rates and the magnesium coefficients
(z) of ginkgo leaves (Ginkgo biloba L.). Our studies were
carried out on ginkgo leaves collected from male and female trees
at different times from two Botanical Gardens in Budapest and
Szeged in Hungary.
Our results showed that the magnesium, calcium, sodium and
potassium contents were always higher in the male samples than in
female ones, except one when the calcium content was lower in the
male samples originated from Szeged. We have detected the highest
potassium content in the Szeged samples because of salting for
preventing icing in the town.
We have found that the magnesium content of leaves was high and
increased in the same way during the experimental time
independently of the growing sites and the sexes of trees (in May
about 3000 µg/g and in September 5000-6000 µg/g).
The magnesium coefficients were increased from May to September,
in May were around 0,08 and in September from 0,08 to 0,14.
According to “z” coefficients the Ginkgo biloba trees are
not magnesium sensitive plants but we have found more information
about the plant using as therapeutic agent in modern
pharmacology.
Key words: Ginko biloba leaves, calcium,
magnesium, potassium, sodium
Ionic relationships between macroelements in yellow lupine
depending on cadmium
contamination and magnesium fertilization of soil
Miros aw Wyszkowski
Dr in.¿ Miros aw Wyszkowski, Katedra Chemii Oerodowiska,
Uniwersytet Warmiñsko-Mazurski w Olsztynie, pl. £ódzki 4,
10-718 Olsztyn, Poland
The aim of the research was to investigate the effect of cadmium
contamination (10, 20, 30 and 40 mg
Cd ?kg-1) and magnesium fertilization
(50 and 100 mg Mg ?kg-1 of
soil) on ionic relationships and distribution of macroelements in
yellow lupine.
High cadmium rates (40 mg
Cd ?kg-1) narrowed the ionic ratios
between Ca :Mg, K :Ca, K :Mg,
K :(Ca + Mg) and K :Na in aboveground organs
and between K :Ca, K :(Ca + Mg) and K :Na
in roots of yellow lupine. Under the influence of magnesium
fertilization the value of ionic ratios between Ca :Mg,
K :Ca, K :Mg, K : (Ca + Mg) decreased both
in aboveground parts and in roots of yellow lupine. In general, the
value of ionic ratios was positively correlated with the yield of
yellow lupine and nearly always negatively correlated with the rate
of Cd and Mg, the content of macroelements in plants and some
physicochemical properties of soil. Soil contamination by cadmium
and magnesium fertilization did not cause much diversification in
the distribution of macroelements in aboveground organs and roots
of yellow lupine.
Key words: cadmium contamination, magnesium
fertilization, yellow lupine, ionic relationship, macroelements
distribution
Effect of nutrition on magnesium content in the hair of primary
school children from the Podlasie region
Jan Karczewski*, Jolanta Lewko, Barbara
Smorczewska-Czupryñska
* Jan Karczewski, Zak ad Higieny i Epidemiologii AM, ul.
Mickiewicza 2c,15-222 Bia ystok, Poland
A total of 2161 children from the Podlasie region aged
12-15 years were involved in the study. The quality of
nutrition was evaluated and Mg content in the hair was determined
by the method of atomic absorption spectrometry. The type of diet
did not significantly affect Mg content in the hair of the children
examined.
Key words: magnesium, hair, children, nutrition
Effect of reactive oxygen species (ROS) on human sperm cells :
The role of magnesium and zinc content of seminal plasma
Sándor A. Kiss*, Zoltán Závaczki, János Szöllõsi, Sándor
Koloszár, Anna Csikkel-Szolnoki
* Sándor A. Kiss, H-6725 Szeged, Fö fasor 73A/2
The success of oocyte fertilization highly depends on presence
of high number of motile, structurally and functionally intact
sperm cells in the ejaculate. There is positive correlation between
sperm concentration and magnesium content of seminal plasma.
According to the literature and our data we can conclude that both
Mg and Zn have effect of fertility of sperm cells.
The best sperm characteristics were found when the Mg and Zn level
were 4/6 nM.1-1, respectively and the Mg :Zn molar ratio
is 1 :2. Human and animal experiments demonstrate the
favorable effect of Mg on male fertility. Since free radicals
damage sperm cells, there is an inverse correlation between ROS and
sperm motility. Correlation between motility and Mg content of
ejaculate shows a bell-shaped curve, the correlation between LPO
(Lipid peroxidation) or ROS (Reactive oxygen species) and Mg level
show an inverse bell-shaped curve.
We also concluded that Mg level of ejaculate (0,7/1,0 nM.1-1)
is 3-10-fold higher than in blood serum.
Key words: reactive oxygen species, human sperm,
magnesium, zinc
LiChroprep RP-8 modified with Orange 7 Acid in trace analysis
of some metal ions
Ryszard Kocjan*, Ireneusz Sowa, El¿bieta
Blicharska
* dr hab. (prof. AM) Ryszard Kocjan, Katedra I Zak ad Chemii
Nieorganicznej i Analitycznej AM w Lublinie, ul. Staszica 6,
20-081 Lublin, Poland, e-mail :
blazewic@panaceum.am.lublin.pl
New chelating sorbent for metal ions was prepared by the
impregnation of chemically modified silica LiChroprep
RP-8 with ion pairs composed of cation of Aliquat 336 and
anion of Orange 7 Acid. The sorbent was compared with
analogous sorbent with plain silica carrier containing the same ion
pairs. The hypothetical molecular mechanism of binding this ion
pair by the surface of the applied carrier was presented. Higher
stability of this sorbent in comparison to that of the plain silica
chelating sorbent was demonstrated. The sorbent obtained was
applied for chromatographic separations of some mixtures of metal
ions and for additional purification of aqueous solutions of
magnesium salts from trace amounts of heavy metals (Cu, Pb, Cd and
Zn).
Key words: Orange 7 Acid, LiChroprep RP-8, chelating
sorbent, Aliquat 336, extraction chromatography, purification of
magnesium salt
Concentration of ionized magnesium in serum in adults from
Szczecin
Tadeusz Kozielec*, Lilia Kotkowiak, Jacek Brodowski, Beata
Karakiewicz, Iwona Hornowska
* Prof. dr hab. med. Tadeusz Kozielec, Katedra i Zak ad
Medycyny Rodzinnej PAM w Szczecinie, ul. Podgórna 22/23,
70-205 Szczecin, Poland, e-mail : koztad@sci.pam.szczecin.pl
The aim of this study was to estimate concentration of ionized
Mg (iMg) in serum of adult people from Szczecin. The study was
conducted on 530 persons (307 men and 223 women)
aged 18 to 90 years. The average age in the group
examined was 47.0 years. Serum level iMg was assessed by AVL
analyzer with ionoselective electrode. All results were
statistically analyzed. Concentration of iMg in the whole group
amounted from 0,33 to 0,99 mmol·dm-3 (mean
concentration 0,56 mmol·dm-3). In the subgroup of
men the mean concentration was 0,55 mmol·dm-3
(range 0,36-0,91 mmol·dm-3). In women the mean
level of iMg was 0,57 mmol·dm-3 (range
0,33-0,99 mmol·dm-3). No statistical difference in
the concentration of iMg between men and women was found. We also
assessed serum iMg in 3 subgroup :
I – 18-40 years old (209 persons) ;
II – 41-60 years old (173 persons) ;
III – 61-90 years old (148 persons).
Mean concentrations in these subgroups were :
I – 0,55 mmol.dm-3,
II – 0,57 mmol.dm-3,
III – 0,58 mmol.dm-3.
No statistical difference was found between any of the
subgroups.
Conclusion : Age and sex have no influence on concentration
of ionized magnesium in serum.
Key words: ionized magnesium, serum, adult
Content of Mg, Ca, Na in potato tubers cultivated using
different weed control methods
Krystyna Zarzecka, Barbara G Siorowska
* Katedra Szczegó owej Uprawy Roœlin AP w Siedlcach, ul.
Prusa 14, 08-110 Siedlce, Poland
The field experiment was conducted at the Experimental Station
Zawady in 1995-1997. The experiment was conducted by means of
randomized sub-blocks with three replications. Six weed control
methods were the lst order factors and four varieties
were the 2nd order factors. The magnesium content in
potato tubers depended only on the weed control methods and the
calcium and sodium concentrations depended on genetic characters of
potatoes. The content of macroelements (Mg, Ca, Na) varied
significantly due to the weather conditions in particular
years.
Key words: magnesium, calcium, sodium, potato, cultivars,
weed control methods
|
Printable version